Osteoarthritis is the most common reason patients undergo knee surgery. TRANSCOLLATION™ technology can contribute to improved surgical outcomes by minimizing blood loss during the surgical procedure. In many cases, a tourniquet is used to prevent bleeding during surgery, which compromises vessels and may contribute to post-operative bleeding. This may increase pain and swelling at the surgical site and minimize range of motion, which could increase the patient's stay in the hospital and be a factor to a longer rehabilitation.

TRANSCOLLATION technology provides better clinical outcomes to patients undergoing knee surgery by reducing bleeding and blood loss. Surgical applications where the AQUAMANTYS® System is often used include:

• Total Knee Replacements
• Revisions
• Bilaterals
• Unicompartmentals

Whether it is treating areas actively bleeding during surgery or treating areas likely to bleed after surgery, the AQUAMANTYS® System preserves the patient's own hemoglobin levels, therefore reducing the risk of transfusion and the need for pre-donation. Less bleeding also reduces the need for a postoperative drain. In addition, bleeding can contribute to increased pain and swelling during recovery.

Patients treated with the AQUAMANTYS System may experience:

• Less pain and swelling
• Improved range of motion
• Reduced time in the hospital
• Reduced infections due to minimized blood transfusions

AQUAMANTYS® System in Total Knee Arthroplasty

• A New Look at Blood Transfusion: Evaluation of the risks and benefits prompts careful blood management. Joint Commission Perspectives on Patient Safety, January 2007, Volume 7, Issue 1.

• Bertone A, Lipson D, Kamei J, Litsky A, Weisbrode S. Effective Bone Hemostasis and Healing Using Radiofrequency and Conductive Fluid. Clin Orthop Relat R 2006 May; 446:278-285

• Rosenberg AG. Reducing blood loss in total joint surgery with a saline-coupled bipolar sealing technology. J Arthroplasty. 2007; 22(4 Suppl 1):82-5.

• Mont MA, Marulanda GA, Ulrich SD, Seyler TM, Delanois RE. Reductions in blood loss with a bipolar sealer in total hip arthroplasty. Expert Rev Med Devices. 2008; 5:125-131.

• Krebs VE, Higuera C, Barsoum WK, Helfand R. Blood Management in Joint Replacement Surgery: What’s in and What’s Out. Orthopedics 2006; 29:801.

• Weeden SH, Schmidt RH, Isabell G. Haemostatic efficacy of a bipolar sealing device in minimally invasive total knee arthroplasty (Abstract). 8th Congress Of The European Federation Of National Associations Of Orthopaedics And Traumatology, 2007. Florence, Italy.

• Rosen MJ. Transcollation technology for primary total joint replacement: Clinical and economic benefits. Data on file.